Paclitaxel

From the bark of yew of a compound. Is the specificity of microtubules stabilizer, can promote the microtubules of assembly and maintain stable microtubules.

The pacltitaxel taxol is a complex of secondary metabolites, is currently know only one can promote microtubules polymerization and stability of the drugs already polymerization microtubules. Isotope tracer, paclitaxel with only that the polymerization, tiny tubes and polymerization of microtubules protein dimers reaction. Cells in cells after contact with taxol accumulated plenty of microtubules within these tiny tubes, the accumulation of various function of cells jamming cell division, especially to stop in mitosis, blocked the normal cell division. Through the Ⅱ - Ⅲ clinical research, paclitaxel mainly suitable for breast, oarian and lung cancer, colon cancer, melanoma, head and neck cancer, leukemia, brain also have certain curative effect.