Tobramycin Basic information
Product Name: Tobramycin
Synonyms: 1-epitobramycin;3’-deoxykanamycinb;4-[2,6-diamino-2,3,6-trideoxy-alpha-d-glycopyranosyl]-6-[3-amino-3-deoxy-alpha;6-trideoxy-alpha-d-ribo-hexopyranosyl-(1-4))-2-deoxy-;d-6-trideoxy-alpha-d-ribohexopyranosyl-(1-6))-2-deoxy;d-6-tyrideoxy-alpha-d-ribohexopyranosyl-(1-6))-2-deoxy;deoxykanamycinb;-d-glycopyranosyl]-2-deoxystreptamine
CAS: 32986-56-4
MF: C18H37N5O9
MW: 467.51
Appearance: white or off-white hygroscopic powder
Pharmacological effects: tobramycin to join in the 30S and 50S of the link position, hindering the formation of 70S complexes, so that mRNA is not translated into proteins, leading to cell death. Mainly against Gram-negative bacteria, such as Pseudomonas aeruginosa, Escherichia coli, Klebsiella, Enterobacter, Proteus, Citrobacter effective. The main clinical sensitivity for serious infections caused by bacteria, such as Gram-negative bacteria, especially Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae infections caused by burns, sepsis, respiratory infections, urinary tract infections, gallbladder and biliary tract infection severe soft tissue infections and so on.
Quality Standard: USP31.
|
