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Sulfobutyl Ether-β-cyclodextrin
Abbreviate: SBE-β-CD
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Compound
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R1
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R2
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R3
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2-O-sulfobutyl-β-CD
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sulfobutyl
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H
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H
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6-O- sulfobutyl -β-CD
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H
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H
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sulfobutyl
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2,3,6-tri-O- sulfobutyl -β-CD
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sulfobutyl
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sulfobutyl
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sulfobutyl
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Features and applications:
SBE-β-CD is a high water-soluble anionic cyclodextrin derivative. It can easily form non-covalent inclusion complexes with drug molecules, thus it has the good perf
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【Sulfobutyl Ether-β-Cyclodextrin Sodium(SBE-β-CD)】
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|
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Sulfobutyl Ether-β-cyclodextrin
Abbreviate: SBE-β-CD
|
Compound
|
R1
|
R2
|
R3
|
|
2-O-sulfobutyl-β-CD
|
sulfobutyl
|
H
|
H
|
|
6-O- sulfobutyl -β-CD
|
H
|
H
|
sulfobutyl
|
|
2,3,6-tri-O- sulfobutyl -β-CD
|
sulfobutyl
|
sulfobutyl
|
sulfobutyl
|
Features and applications:
SBE-β-CD is a high water-soluble anionic cyclodextrin derivative. It can easily form non-covalent inclusion complexes with drug molecules, thus it has the good performances in enhancing drug stability, solubility and safety, reducing drug toxicity and hemolysis, covering up bad smell, and controlling drug release rate.
SBE-β-CD has been used in injection, oral, nasal and eye medication. Modification by charged functional units can improve the binding affinity of cyclodextrins for oppositely charged guests, so it has a special affinity for drugs with nitrogen elements.
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ormances in enhancing drug stability, solubility and safety, reducing drug toxicity and hemolysis, covering up bad smell, and controlling drug release rate.
SBE-β-CD has been used in injection, oral, nasal and eye medication. Modification by charged functional units can improve the binding affinity of cyclodextrins for oppositely charged guests, so it has a special affinity for drugs with nitrogen elements.
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