mp :213 °C (dec.)(lit.)
refractive index : -49 ° (C=1, MeOH)
storage temp.:2-8°C
solubility methanol: 50 mg/mL, clear, colorless
Usage :An antineoplastic. Used in the study of structure and function of microtubles into tubulin General Description: Needles (from aqueous methanol) or fine white powder. An anti-cancer drug. Air & Water Reactions: May be sensitive to prolonged exposure to moisture. . Health Hazard: TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. Fire Hazard :Flash point data for Paclitaxel are not available. Paclitaxel is probably combustible. Biological Activity :Antitumor agent; promotes and stabilizes tubulin polymerization, causing cell cycle arrest. Induces autocatalytic activation of caspase-10 in CCRF-HSB-2 cells, triggering apoptosis.
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