Colchicine [CAS No.]64-86-8 [Molecular formula and molecular weight] C22H25NO6; 399.44 [Main specification] 98% test by HPLC [Pharmacology function] Colchicine is a highly poisonous natural product and secondary metabolite, originally extracted from plants of the genus Colchicum Autumn crocus, Colchicum autumnale, also known as the "Meadow saffron"). Originally used to treat rheumatic complaints and especially gout, it was also prescribed for its cathartic and emetic ffects. Its present medicinal use is mainly in the treatment of gout; as well, it is being investigated for its potential use as an anti-cancer rug. It can also be used as initial treatment for pericarditis and preventing recurrences of the condition. In neurons, axoplasmic transport is disrupted by colchicine.
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