Colchicine

Name Colchicine
CAS No 64-86-8
Purity Colchicine 98% Tested By HPLC
Herb SourceFrom the bulb of the Colchicumautumata L.
Molecular Formula C22H25NO6
Molecular Weight 399.44
Brief Light yellow crystal. smellless, will change dark yellow when exposed to the light.
Solubility1g Colchicine solved in 22ml water, in 220ml aethers or 100ml benzene ,sparing

soluble in alcohols and chloroform. Insoluble in petroleum ether.
Optical rotation-250° (c=1, alcohol)
Pharmacology
This product plays as anti-gout, anti-tumor, inhibiting the mitotic cell stopping in M phase. It has the significant effects on breast cancer, cervical cancer, esophageal

cancer, lung cancer, gastric cancer and chronic myelogenous leukemia. It also can be used for acute gout, antiinflammatory analgesic.

In recent years ,furtherly expand its clinical application, for example:to prevent atherosclerosis damage;to cure the liver cirrhosis;

to relief the cycle heat caused by abnormal catecholamine, the Behcet's disease; the lumbar disc herniation,intractable waist pain and

sciatica;prevent intestine adhesion. In addition, its used as the treatment of Purple epilepsy caused thrombocytopenia; Persistent

apophysis erythema; Advanced schistosomiasis; idiopathic pulmonary fiber inflammation; systemic lupus of erythema(SLE) .Moreover, using colchicine three can get the polyploidy,so Colchicine is indispensable in chromosome research.