▲Camptothecin
【Chemical name】 4-Ethyl-4-hydroxy-1H-pyrano-[3 ', 4': 6,7] indolizino [1,2-b] quinoline-3, 14 (4H, 12H)-dione
【Source】 involucrata plants plant Camptotheca acuminata fruit, leaves, roots.
【Content】 HPLC ≥ 99%
【Loss on drying】 ≤ 0.5%
【Molecular formula】 C20H16N2O4
【Molecular weight】 348.36
【Physical and Chemical Properties】 light yellow needle crystal (methanol - acetonitrile), decomposition point: 264 ℃ ∽ 267 ℃, [α] 25D +31.3. (Chloroform - methanol). Strong performance in the blue under ultraviolet fluorescence, and acid can not form a stable salt.
【Application】 used in clinical cancer, psoriasis, warts treatment, acute and chronic leukemia and other Hepatosplenomegaly caused by schistosomiasis.
【Product Description】 camptothecin is one of ours flagship product , which species extracted by something called acuminata (also known as qianzhang tree) with leaves, fruit , and each process through a strict quality control, finally get high-purity products.
Camptothecin and its molecular structure shown in Figure
Camptothecin (called CPT for short) is a cytotoxic natural alkaloid, The first time in 1966, the Wall and others separated it from involucrata plants Camptotheca acuminata of the rod and the skin. Continuous molecular structure of conjugated rings, containing a pyrrolo [3,4-b] quinoline ring (ring A, B, C), a conjugate of α-pyridone ring (ring D) and a six α-hydroxy lactone ring (ring E), the only chiral molecule C20 to S-type. |