CAS: 81403-68-1 MF: C19H28ClN5O4 MW: 425.91 Product Categories: APIs;Antihypertensive;Antihypertensive, Treatment of BPH;Intermediates & Fine Chemicals;Pharmaceuticals;Alfuzosin mp :225°C Chemical Properties: White to Off-White Solid Usage: a-1- Adrenoceptor antagonist structurally similar to prozosin Biological Activity :Functionally uro-selective α 1 adrenoceptor antagonist that does not discriminate between α 1 subtypes. Inhibits increases in intraurethral pressure caused by phenylephrine-induced contraction by 81% with minor cardiovascular effects. Also relaxes corpus cavernosum tissue (pIC 50 = 7.64) in vitro .
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