4-Acetylamino-N-(2'-aminophenyl)benzamide Synonyms: 4-acetylamino-n-(2'-aminophenyl)benzamide;Benzamide, 4-(acetylamino)-N-(2-aminophenyl)-;acetyldinaline;Tacedinaline;CI 994;N-Acetyldinaline CAS: 112522-64-2 MF: C15H15N3O2 MW: 269.3 Biological Activity :Orally active histone deacetylase (HDAC) inhibitor (K i values are 0.41, 0.75, >100 and >100 μ M for HDAC1, HDAC3, HDAC6 and HDAC8 respectively). Mediates G 1 cell cycle arrest, inhibits proliferation and induces apoptosis in vitro and in vivo .
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